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A Level biology explained

Five specifications, three boards, one A Level. This page walks through what's on each paper, what's allowed in the exam, how the marks are split, and the specification codes if you need to check anything with the school.

Video coming soon The written guide below is complete and ready to read.

One of these qualifications is being withdrawn

  • OCR B — Biology B (Advancing Biology) (H422) — OCR is withdrawing this qualification. The final first teach date was September 2026 and the final assessment opportunity is summer 2028. There is no resit opportunity

If your child is taking it, this matters: there is no resit after the final series. A student who misses or fails the exam cannot retake the same qualification.

The other 4 specifications on this page continue as normal. If you are unsure which one your child is entered for, the school office will tell you.

The exam boards compared

There are 5 A Level biology specifications in England. The boards do not teach different biology, what changes is how the course is organised. Your child’s school chooses which one to enter, and it may not be the same board it uses for other subjects. If you do not know which one, the school office will tell you.

At a glance

AQAEdexcel A — Biology A (Salters-Nuffield)Edexcel B — Biology B
Specification code74029BN09BI0
Papers333
Length of each2 hr / 2 hr / 2 hr2 hr / 2 hr / 2 hr1 hr 45 min / 1 hr 45 min / 2 hr 30 min
Marks per paper91 / 91 / 78100 / 100 / 10090 / 90 / 120
Total marks260300300
Weighting35% / 35% / 30%33.33% / 33.33% / 33.33%30% / 30% / 40%
OCR A — Biology AOCR B — Biology B (Advancing Biology)
Specification codeH420H422
Papers33
Length of each2 hr 15 min / 2 hr 15 min / 1 hr 30 min2 hr 15 min / 2 hr 15 min / 1 hr 30 min
Marks per paper100 / 100 / 70110 / 100 / 60
Total marks270270
Weighting37% / 37% / 26%41% / 37% / 22%

What is on each paper

AQAEdexcel A — Biology A (Salters-Nuffield)Edexcel B — Biology B
Paper 1Topics 1 to 4The Natural Environment and Species SurvivalAdvanced Biochemistry, Microbiology and Genetics
Paper 2Topics 5 to 8Energy, Exercise and Co-ordinationAdvanced Physiology, Evolution and Ecology
Paper 3Topics 1 to 8, plus the essayGeneral and Practical Applications in BiologyGeneral and Practical Principles in Biology
OCR A — Biology AOCR B — Biology B (Advancing Biology)
Paper 1Biological processesFundamentals of biology
Paper 2Biological diversityScientific literacy in biology
Paper 3Unified biologyPractical skills in biology

AQA does not give its papers names. What each paper covers is shown instead.

In the exam

AQAEdexcel A — Biology A (Salters-Nuffield)Edexcel B — Biology B
Data or formulae sheetNot stated in the specificationNot stated in the specificationNot stated in the specification
Required practicals121816
Practical endorsementSeparate, does not affect the gradeSeparate, does not affect the gradeSeparate, does not affect the grade
OCR A — Biology AOCR B — Biology B (Advancing Biology)
Data or formulae sheetNot stated in the specificationNot stated in the specification
Required practicals1212
Practical endorsementSeparate, does not affect the gradeSeparate, does not affect the grade

Every board sets a number of compulsory practicals, but they do not count them the same way, so the figures are not directly comparable: AQA lists required practicals, Edexcel core practicals, and OCR groups its into Practical Activity Groups. The practical endorsement is reported separately and does not contribute to the A level grade, but a student must complete it to be awarded the qualification.

How the marks are awarded

Whichever board your child sits, the exam rewards the same kinds of thinking in almost the same proportions. About a third of the marks are for straightforward recall (knowing the facts). A little over 40% are for applying that knowledge to a new question. The remaining quarter or so is for analysing, interpreting and evaluating (the harder skills).

Every board also sets a minimum for mathematical content: 10% of the marks in A Level biology are for maths at GCSE higher tier standard or above.

Codes, if you need to check with the school

AQAEdexcel A — Biology A (Salters-Nuffield)Edexcel B — Biology B
Specification code74029BN09BI0
Ofqual number601/4625/4601/5299/0601/5301/5
Checked againstversion 1.6, July 2026Issue 4, November 2018Issue 4, November 2018
OCR A — Biology AOCR B — Biology B (Advancing Biology)
Specification codeH420H422
Ofqual number601/4260/1601/4720/9
Checked againstversion 4.1, April 2026version 3.2, April 2026

Every figure above was read from the board’s own specification on the date shown. Specifications change; if you are making a decision on one of these, confirm it with the school.